Publications

Nano Research (2026) · Review

Toward brain-wide lifetime electrophysiology at single-cell single-spike resolution in mammals via implantable microelectronics

H. Sheng, P. Le Floch, T. S. Blum, J. Liu

Nature 642, 954–964 (2025)

Brain implantation of soft bioelectronics via embryonic development

Hao Sheng#, Ren Liu#, Qiang Li#, Zuwan Lin#, Yichun He, Thomas S. Blum, Hao Zhao, Xin Tang, Wenbo Wang, Lishuai Jin, Zheliang Wang, Emma Hsiao, Paul Le Floch, Hao Shen, Ariel J. Lee, Rachael Alice Jonas-Closs, James Briggs, Siyi Liu, Daniel Solomon, Xiao Wang, Jessica L. Whited, Nanshu Lu, Jia Liu

• Cover article · Nature ↗

Mechanics of Materials 188, 104844 (2024)

A shear-lag model for laminated beams with extreme modulus mismatch between layers

Z. Wang, H. Sheng, X. Lin, Y. Rao, J. Liu, N. Lu

Nature Nanotechnology 19, 319–329 (2024)

3D spatiotemporally scalable in vivo neural probes based on fluorinated elastomers

P. Le Floch, S. Zhao, R. Liu, N. Molinari, E. Medina, H. Shen, Z. Wang, H. Sheng, S. Partarrieu, W. Wang, C. Sessler, G. Zhang, H. Park, X. Gong, A. Spencer, J. Lee, T. Ye, X. Tang, X. Wang, K. Bertoldi, N. Lu, B. Kozinsky, Z. Suo, J. Liu

Cell 186, 2002–2017.e21 (2023)

Multimodal charting of molecular and functional cell states via in situ electro-sequencing

Q. Li, Z. Lin, R. Liu, X. Tang, J. Huang, Y. He, X. Sui, W. Tian, H. Shen, H. Zhou, H. Sheng, H. Shi, L. Xiao, X. Wang, J. Liu

• Cover article · Cell ↗

Science Advances 9, eade8513 (2023)

Tissue-embedded stretchable nanoelectronics reveal endothelial cell-mediated electrical maturation of human 3D cardiac microtissues

Z. Lin, J. C. Garbern, R. Liu, Q. Li, E. Juncosa, H. Elwell, M. Sokol, J. Aoyama, U. Deumer, E. Hsiao, H. Sheng, R. T. Lee, J. Liu

Nature Neuroscience 26, 430–446 (2023)

Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer's disease

H. Zeng, J. Huang, H. Zhou, W. J. Meilandt, B. Dejanovic, Y. Zhou, C. J. Bohlen, S. Lee, J. Ren, A. Liu, Z. Tang, H. Sheng, J. Liu, M. Sheng, X. Wang

Biomaterials 281, 121352 (2022)

Subdural neural interfaces for long-term electrical recording, optical microscopy and magnetic resonance imaging

X. Wang#, M. Wang#, H. Sheng#, L. Zhu, J. Zhu, H. Zhang, Y. Liu, L. Zhan, X. Wu, Z. Suo, W. Xi, H. Wang

Extreme Mechanics Letters 38, 100742 (2020)

Polymer-filled macroporous hydrogel for low friction

R. Mu, J. Yang, Y. Wang, Z. Wang, P. Chen, H. Sheng, Z. Suo

Extreme Mechanics Letters 30, 100510 (2019)

Neural interfaces by hydrogels

H. Sheng, X. Wang, N. Kong, W. Xi, H. Yang, X. Wu, K. Wu, C. Li, J. Hu, J. Tang, J. Zhou, S. Duan, H. Wang, Z. Suo

Nano Letters 19, 5781–5789 (2019)

Cyborg organoids: implantation of nanoelectronics via organogenesis for tissue-wide electrophysiology

Q. Li, K. Nan, P. Le Floch, Z. Lin, H. Sheng, T. S. Blum, J. Liu

Small 15, 1804651 (2019)

Self-healing, adhesive, and highly stretchable ionogel as a strain sensor for extremely large deformation

L. M. Zhang, Y. He, S. Cheng, H. Sheng, K. Dai, W. J. Zheng, M. X. Wang, Z. Chen, Y. Chen, Z. Suo